Isoniazid Ampoules 50mg / 2ml (Cambridge Laboratories)

1. Name Of The Medicinal Product

Isoniazid Ampoules 50 mg/2 ml.

2. Qualitative And Quantitative Composition

Each ampoule contains 50 mg Isoniazid BP in 2 ml of solution.

3. Pharmaceutical Form

Ampoules

4. Clinical Particulars

4.1 Therapeutic Indications

For all forms of pulmonary and extra-pulmonary tuberculosis.

4.2 Posology And Method Of Administration

Isoniazid ampoules are for intramuscular, intravenous, intrapleural, or intrathecal injection.

Adults and children

The usual intramuscular or intravenous dose for adults is 200 to 300 mg as a single daily dose, for children 100 to 300 mg daily (10 - 20 mg/kg), but doses much larger than these are sometimes given, especially in conditions such as tuberculous meningitis. It is recommended to give an intravenous dose slowly as an undiluted bolus injection, although other methods may be employed.

Neonates

The recommended intravenous or intramuscular dose for neonates is 3-5 mg/kg with a maximum of 10 mg/kg daily. Isoniazid may be present in the milk of lactating mothers.

The elderly

No dosage reduction is necessary in the elderly.

Intrapleural use

50 to 250 mg may be instilled intrapleurally after aspiration of pus, the dosage of oral isoniazid on that day being correspondingly reduced. The ampoule solution is also used for the local treatment of tuberculous ulcers, for irrigation of fistulae, etc.

Intrathecal use:

It should be noted that CSF concentrations of isoniazid are approximately 90% of plasma concentrations. Where intrathecal use is required, 25 - 50 mg daily has been given to adults and 10 - 20 mg daily for children, according to age.

It is usual to give Isoniazid together with other antituberculous therapy, as determined by current practice and/or sensitivity testing.

It is recommended that pyridoxine 10 - 50mg daily be given during Isoniazid therapy to minimise adverse reactions, especially in malnourished patients and those predisposed to neuropathy (eg. diabetics and alcoholics).

4.3 Contraindications

Isoniazid should not be given to patients with a history of sensitivity to isoniazid.

4.4 Special Warnings And Precautions For Use

Use in renal and hepatic impairment: no dosage reduction of Isoniazid is necessary when given to patients with mild renal failure. Patients with severe renal failure (glomerular filtration rate of less than 10 ml/minute) and slow acetylator status might require a dose reduction of about 100mg to maintain trough plasma levels at less than 1 mcg/ml. The possible risks of administration of Isoniazid to patients with pre-existing non-tuberculous hepatic disease should be balanced against the benefits expected from treating tuberculosis.

Care is also required in chronic alcoholism and when prescribing isoniazid for patients with pre-existing hepatitis. Convulsions and psychotic reactions have occurred, especially in patients with a previous history of these conditions. These manifestations usually subside rapidly when the drug is withdrawn. Isoniazid should therefore be given with caution to patients with convulsive disorders and should be avoided in those with manic or hypomanic psychoses.

Isoniazid is metabolised by acetylation, which is subject to genetic variation. The 'slow acetylators' may be more susceptible to drug-induced peripheral neuropathy. However, dose adjustment is not normally required.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

Isoniazid may inhibit the metabolism of phenytoin, primidone and carbamazepine. Plasma levels of these drugs should be monitored if concurrent therapy with Isoniazid is necessary. See also statement under 4.8 regarding Rifampicin.

4.6 Pregnancy And Lactation

While Isoniazid is generally regarded to be safe in pregnancy, there is a possibility of an increased risk of foetal malformations occurring when Isoniazid is given in early pregnancy. If pregnancy cannot be excluded possible risks should be balanced against therapeutic benefits. Isoniazid is excreted in breast milk at concentrations equivalent to

those found in maternal plasma, ie. 6-12 mcg/ml. this could result in an infant ingesting up to 2 mg/kg/day.

4.7 Effects On Ability To Drive And Use Machines

None known.

4.8 Undesirable Effects

Isoniazid is generally well tolerated. Side-effects have been reported mainly in association with high doses or in slow acetylators who develop higher blood levels of the drug. Fever, peripheral neuropathy (preventable with pyridoxine), optic neuritis and atrophy, allergic skin conditions (including erythema multiforme), and rarely lupoid syndrome, pellagra, purpura and haematological reactions have occurred during isoniazid therapy. Hyperglycaemia and gynaeco-mastia have been reported with isoniazid treatment. Isoniazid, especially if given with rifampicin, may induce abnormalities in liver function, particularly in patients with pre-existing liver disorders, in the elderly, the very young and the malnourished. Monthly review is suggested to detect and limit the severity of this side-effect by stopping treatment if plasma transaminases exceed three times the upper limit of normal. There is conflicting opinion as to the relationship of this side-effect to acetylator status.

4.9 Overdose

In severe poisoning the main risk is of epileptiform convulsions. In addition any of the side-effects listed above may occur together with metabolic acidosis and hyperglycaemia. Treatment should be directed to the control of convulsions and large doses of pyridoxine may limit the occurrence of other adverse effects. Metabolic acidosis may require sodium bicarbonate infusion. The drug is removed by dialysis.

5. Pharmacological Properties

5.1 Pharmacodynamic Properties

Isoniazid is a highly active tuberculostatic drug, and at high concentrations it is bactericidal to mycobacterium tuberculosis, possibly acting by interference with the synthesis of mycolic acid (a constituent of the bacterial cell wall).

5.2 Pharmacokinetic Properties

Isoniazid is not appreciably protein-bound and diffuses readily throughout the body. It affects intracellular as well as extracellular bacilli. The primary metabolic route involves acetylation the rate of which is determined genetically.

5.3 Preclinical Safety Data

There are no pre-clinical data of relevance to the prescriber which are additional to that already included in other sections of the SPC.

6. Pharmaceutical Particulars

6.1 List Of Excipients

Hydrochloric Acid

Water for Injections BP

6.2 Incompatibilities

None known.

6.3 Shelf Life

Three years.

6.4 Special Precautions For Storage

The recommended maximum storage temperature is 25°C.

Protect from light.

6.5 Nature And Contents Of Container

Colourless glass ampoules coded with dark red and orange colour rings, each containing 2 ml of solution, in packs of 10 ampoules.

6.6 Special Precautions For Disposal And Other Handling

None.

Administrative Data

7. Marketing Authorisation Holder

Cambridge Laboratories Limited

Deltic House

Kingfisher Way

Silverlink Business Park

Wallsend

Tyne & Wear

NE28 9NX

8. Marketing Authorisation Number(S)

PL 12070/0005

9. Date Of First Authorisation/Renewal Of The Authorisation

30 July 1997

10. Date Of Revision Of The Text

April 2002

Flora-Q

Generic Name: lactobacillus acidophilus (LAK toe ba SIL us AS sid OFF il us)

Brand Names: Acidophilus, Acidophilus Extra Strength, Bacid, Flora-Q 2, Novaflor, RisaQuad, RisaQuad 2, Superdophilus

What is Flora-Q (lactobacillus acidophilus)?

Lactobacillus acidophilus is a bacteria that exists naturally in the body, primarily in the intestines and the vagina. Lactobacillus acidophilus helps maintain an acidic environment in the body, which can prevent the growth of harmful bacteria.

Lactobacillus acidophilus has been used to treat or prevent vaginal yeast infections, yeast infections of the mouth, diarrhea caused by taking antibiotics, and urinary tract infections. Lactobacillus acidophilus may work by helping the body maintain normal consistency of bacteria in the stomach, intestines, and vagina.

Lactobacillus acidophilus has not been approved by the FDA to treat any disease, and it should not be substituted for prescription medications.

Lactobacillus acidophilus has not been evaluated by the FDA for safety, effectiveness, or purity. All potential risks and/or advantages of lactobacillus acidophilus may not be known. Additionally, there are no regulated manufacturing standards in place for these compounds. Some marketed herbal supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Lactobacillus acidophilus may also have be used for other purposes not listed in this product guide.

What is the most important information I should know about Flora-Q (lactobacillus acidophilus)?

Lactobacillus acidophilus has not been approved by the FDA to treat any disease, and it should not be substituted for prescription medications.

Lactobacillus acidophilus has not been evaluated by the FDA for safety, effectiveness, or purity. All potential risks and/or advantages of lactobacillus acidophilus may not be known. Additionally, there are no regulated manufacturing standards in place for these compounds. Some marketed herbal supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Talk to your doctor before taking lactobacillus acidophilus if you have any other medical conditions, allergies, or if you take other medicines or herbal/health supplements. Under certain conditions, it may be dangerous for you to take lactobacillus acidophilus.

Do not take lactobacillus acidophilus without first talking to your doctor if you are pregnant or may become pregnant during treatment. Do not take lactobacillus acidophilus without first talking to your doctor if you are breast-feeding a baby. Do not give any herbal/health supplement to a child without the advice of a doctor.

What should I tell my healthcare provider before taking Flora-Q (lactobacillus acidophilus)?

Talk to your doctor before taking lactobacillus acidophilus if you have any other medical conditions, allergies, or if you take other medicines or herbal/health supplements. Under certain conditions, it may be dangerous for you to take lactobacillus acidophilus.

Do not take lactobacillus acidophilus without first talking to your doctor if you are pregnant or may become pregnant during treatment. Do not take lactobacillus acidophilus without first talking to your doctor if you are breast-feeding a baby. Do not give any herbal/health supplement to a child without the advice of a doctor.

How should I take Flora-Q (lactobacillus acidophilus)?

When considering the use of herbal supplements, seek the advice of your doctor. You may also consider consulting a practitioner who is trained in the use of herbal/health supplements.

Do not take more of this product than is directed.

If you choose to take lactobacillus acidophilus, use it as directed on the package or as directed by your doctor, pharmacist, or other healthcare provider. Do not use more of this product than is recommended on the label.

Lactobacillus acidophilus is available in capsule and tablet form. Powder or liquid forms may also be available. Some dairy products, especially yogurt, also contain lactobacillus acidophilus.

Do not use many different forms (such as tablets, topical formulations, and others) of lactobacillus acidophilus at the same time, unless your healthcare professional has told you to. You may get too much of this product if you use different forms together.

Store lactobacillus acidophilus in a sealed container as directed on the product label, away from moisture, heat, and light.

What happens if I miss a dose?

No information is available about missing a dose of lactobacillus acidophilus. Consult your doctor, pharmacist, or healthcare provider for instructions if you miss a dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Flora-Q (lactobacillus acidophilus)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using lactobacillus acidophilus.

Flora-Q (lactobacillus acidophilus) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Less serious side effects may be more likely, and you may have none at all.

Tell your doctor, pharmacist, herbalist, or other healthcare provider about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Flora-Q (lactobacillus acidophilus)?

There may be other drugs that can interact with lactobacillus acidophilus. Tell your healthcare provider about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your healthcare provider.

More Flora-Q resources

• Flora-Q Support Group
• 0 Reviews for Flora-Q - Add your own review/rating

• Lactobacillus Acidophilus Monograph (AHFS DI)


• Acidophilus Natural MedFacts for Professionals (Wolters Kluwer)


• Acidophilus Natural MedFacts for Consumers (Wolters Kluwer)


• Acidophilus Consumer Overview

Compare Flora-Q with other medications

• Clostridial Infection
• Diarrhea
• Irritable Bowel Syndrome
• Oral Thrush
• Traveler's Diarrhea
• Urinary Tract Infection
• Vaginal Yeast Infection

Where can I get more information?

• Consult with a licensed healthcare professional before using any herbal/health supplement. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments.

thioguanine

thye-oh-GWA-neen

Available Dosage Forms:

• Tablet

Therapeutic Class: Antineoplastic Agent

Pharmacologic Class: Antimetabolite

Uses For thioguanine

Thioguanine belongs to the group of medicines known as antimetabolites. It is used to treat some kinds of cancer.

Thioguanine interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by thioguanine, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects may not be serious but may cause concern. Some effects may not occur for months or years after the medicine is used.

Before you begin treatment with thioguanine, you and your doctor should talk about the good thioguanine will do as well as the risks of using it.

Thioguanine is available only with your doctor's prescription.

Before Using thioguanine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For thioguanine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to thioguanine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Children are especially sensitive to the effects of thioguanine. This may increase the chance of liver toxicity during treatment.

Geriatric

Many medicines have not been tested in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information about the use of thioguanine in the elderly.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	D	Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking thioguanine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using thioguanine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Rotavirus Vaccine, Live

Using thioguanine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Adenovirus Vaccine Type 4, Live


• Adenovirus Vaccine Type 7, Live


• Bacillus of Calmette and Guerin Vaccine, Live


• Influenza Virus Vaccine, Live


• Measles Virus Vaccine, Live


• Mumps Virus Vaccine, Live


• Rotavirus Vaccine, Live


• Rubella Virus Vaccine, Live


• Smallpox Vaccine


• Typhoid Vaccine


• Varicella Virus Vaccine


• Yellow Fever Vaccine

Using thioguanine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Busulfan

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of thioguanine. Make sure you tell your doctor if you have any other medical problems, especially:

• Chickenpox (including recent exposure) or


• Herpes zoster (shingles)—Risk of severe disease affecting other parts of the body

• Gout (history of) or


• Kidney stones (history of)—Thioguanine may increase levels of uric acid in the body, which can cause gout or kidney stones

• Infection—Thioguanine can reduce immunity to infection

• Kidney disease or


• Liver disease—Effects may be increased because of slower removal of thioguanine from the body

• Thiopurine methyltransferase deficiency (TPMT)—You may be more sensitive to the side effects of thioguanine, and your doctor may reduce your dose

• Tumors—Thioguanine should not be used if your tumor did not get smaller when previously treated with thioguanine

Proper Use of thioguanine

Take thioguanine only as directed by your doctor. Do not take more or less of it, and do not take it more often than your doctor ordered. The exact amount of medicine you need has been carefully worked out. Taking too much may increase the chance of side effects, while taking too little may not improve your condition.

Thioguanine is sometimes given together with certain other medicines. If you are using a combination of medicines, make sure that you take each one at the right time and do not mix them. Ask your health care professional to help you plan a way to take your medicine at the right times.

While you are using thioguanine, your doctor may want you to drink extra fluids so that you will pass more urine. This will help prevent kidney problems and keep your kidneys working well.

Thioguanine sometimes causes nausea and vomiting. However, it is very important that you continue to take thioguanine, even if you begin to feel ill. Do not stop taking thioguanine without first checking with your doctor. Ask your health care professional for ways to lessen these effects.

If you vomit shortly after taking a dose of thioguanine, check with your doctor. You will be told whether to take the dose again or to wait until the next scheduled dose.

Dosing

The dose of thioguanine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of thioguanine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Missed Dose

If you miss a dose of thioguanine, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Call your doctor or pharmacist for instructions.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using thioguanine

It is very important that your doctor check your progress at regular visits to make sure that thioguanine is working properly and to check for unwanted effects.

While you are being treated with thioguanine, and after you stop treatment with it, do not have any immunizations (vaccinations) without your doctor's approval. Thioguanine may lower your body's resistance and there is a chance you might get the infection the immunization is meant to prevent. Other people living in your household should not take or should not have recently taken oral polio vaccine since there is a chance they could pass the polio virus on to you. Also, avoid other persons who have taken oral polio vaccine. Do not get close to them and do not stay in the same room with them for very long. If you cannot take these precautions, you should consider wearing a protective face mask that covers the nose and mouth.

Thioguanine can lower the number of white blood cells in your blood temporarily, increasing the chance of getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:

• If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.


• Check with your doctor immediately if you notice any unusual bleeding or bruising; black, tarry stools; blood in urine or stools; or pinpoint red spots on your skin.


• Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done.


• Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime.


• Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters.


• Avoid contact sports or other situations where bruising or injury could occur.

thioguanine Side Effects

Along with their needed effects, medicines like thioguanine can sometimes cause unwanted effects such as blood problems and other side effects. These and others are described below. Also, because of the way these medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months or years after the medicine is used. These delayed effects may include certain types of cancer, such as leukemia. Discuss these possible effects with your doctor.

Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Black, tarry stools


• blood in urine or stools


• cough or hoarseness


• fever or chills


• lower back or side pain


• painful or difficult urination


• pinpoint red spots on skin


• unusual bleeding or bruising

Check with your doctor as soon as possible if any of the following side effects occur:

Less common

• Joint pain


• swelling of feet or lower legs


• unsteadiness when walking

Rare

• Sores in mouth and on lips


• yellow eyes or skin

Frequency not determined

• Abdominal or stomach pain


• bloated abdomen


• chest pain or discomfort


• cough or hoarseness


• coughing up blood


• dark urine


• dizziness


• fainting


• fatigue


• headache


• hives


• itching


• light-colored stools


• loss of appetite


• lower back or side pain


• nausea


• pain and fullness in right upper abdomen


• pale skin


• purple- or red-colored spots on body or inside the mouth or nose


• rash


• shortness of breath


• sore throat


• swollen glands


• unpleasant breath odor


• unusual tiredness or weakness


• vomiting


• vomiting of blood


• weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Diarrhea


• loss of appetite


• nausea and vomiting


• skin rash or itching

After you stop using thioguanine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

• Black, tarry stools


• blood in urine or stools


• cough or hoarseness


• fever or chills


• lower back or side pain


• painful or difficult urination


• pinpoint red spots on skin


• unusual bleeding or bruising

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: thioguanine side effects (in more detail)

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More thioguanine resources

• Thioguanine Side Effects (in more detail)
• Thioguanine Dosage
• Thioguanine Use in Pregnancy & Breastfeeding
• Drug Images
• Thioguanine Drug Interactions
• Thioguanine Support Group
• 0 Reviews for Thioguanine - Add your own review/rating

• thioguanine Concise Consumer Information (Cerner Multum)


• Thioguanine Prescribing Information (FDA)


• Thioguanine Monograph (AHFS DI)


• Thioguanine Professional Patient Advice (Wolters Kluwer)


• Thioguanine MedFacts Consumer Leaflet (Wolters Kluwer)


• Tabloid Prescribing Information (FDA)

Compare thioguanine with other medications

• Acute Nonlymphocytic Leukemia

Abilify

Generic Name: aripiprazole (Oral route)

ar-i-PIP-ra-zole

Oral route(Tablet;Tablet, Disintegrating;Solution)

Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of death. Although the causes of death in clinical trials were varied, most of the deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature. Aripiprazole is not approved for the treatment of patients with dementia-related psychosis.Antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults in short-term studies with major depressive disorder (MDD) and other psychiatric disorders. Short term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24, and there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. This risk must be balanced with the clinical need. Monitor patients closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. Not approved for use in pediatric patients with depression .

Commonly used brand name(s)

In the U.S.

• Abilify


• Abilify Discmelt

Available Dosage Forms:

• Tablet


• Tablet, Disintegrating


• Solution

Therapeutic Class: Antipsychotic

Uses For Abilify

Aripiprazole is used to treat nervous, emotional, and mental conditions (e.g., schizophrenia). It may be used alone or together with other medicines (e.g., lithium or valproate) for the acute or maintenance treatment of bipolar I disorder (manic-depressive illness). Additionally, it may be used together with other medicines for the treatment of major depressive disorder (MDD) in adults. It is also used to treat irritability in children 6 to 17 years of age with autistic disorder. This medicine should not be used to treat behavioral problems in older adult patients who have dementia or Alzheimer's disease.

This medicine is available only with your doctor's prescription.

Before Using Abilify

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of aripiprazole in children with schizophrenia younger than 13 years of age and in children with bipolar disorder younger than 10 years of age. Safety and efficacy have not been established in these age groups.

Aripiprazole is not approved for use in children or teenagers with major depression.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of aripiprazole in children with autistic disorder 6 to 17 years of age.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of aripiprazole in elderly patients who have schizophrenia, depression, or bipolar disorder.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Metoclopramide

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Hydromorphone


• Milnacipran

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Carbamazepine


• Clarithromycin


• Ketoconazole


• Quinidine

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Alcohol abuse, history of or


• Depression or


• Drug abuse or dependence, history of or


• Neuroleptic malignant syndrome (NMS), history of or


• Seizures, history of—Use with caution. May make these conditions worse.

• Blood vessel disease or


• Dehydration or


• Heart attack or stroke, history of or


• Heart disease or


• Heart failure or


• Heart rhythm problems or


• Hypotension (low blood pressure) or


• Hypovolemia (decrease in blood volume) or


• Ischemic heart disease, history of or


• Trouble with swallowing—Use with caution. May cause side effects to become worse.

• Diabetes, or family history of or


• Hyperglycemia (high blood sugar)—This medicine may raise your blood sugar levels.

• Phenylketonuria (PKU)—The orally disintegrating tablet contains phenylalanine, which can make this condition worse.

Proper Use of aripiprazole

This section provides information on the proper use of a number of products that contain aripiprazole. It may not be specific to Abilify. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

This medicine should come with a Medication Guide. It is very important that you read and understand this information. Be sure to ask your doctor about anything you do not understand.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not open the blister pack that contains the tablet until you are ready to take it. Remove the tablet from the blister pack by peeling back the foil, then taking the tablet out. Do not push the tablet through the foil. Do not break or split the tablet. Place the tablet in your mouth. It should melt quickly. After the tablet has melted, you may swallow or take a sip of water.

Swallow the tablets whole. Do not break, crush, or chew them.

Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.

Aripiprazole may be taken with or without food. If your doctor tells you to take it a certain way, follow your doctor's instructions.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For bipolar mania:
  
  • For oral dosage forms (tablets and orally disintegrating tablets):
    
    • Adults—At first, 15 milligrams (mg) once a day. When it is given with lithium or valproate, the starting dose is 10 to 15 mg once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day.
    
    
    • Children 10 years of age and older—At first, 2 mg once a day. The dose will be gradually increased to 10 mg once a day. Your doctor may adjust your dose again as needed. However, the dose is usually not more than 30 mg per day.
    
    
    • Children younger than 10 years of age—Use and dose must be determined by your doctor.
    
    
  
  

• For depression:
  
  • For oral dosage forms (tablets, orally disintegrating tablets, and solution):
    
    • Adults—At first, 2 to 5 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 15 mg per day.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  


• For irritability in children with autistic disorder:
  
  • For oral dosage forms (tablets, orally disintegrating tablets, and solution):
    
    • Children 6 to 17 years of age—At first, 2 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 15 mg per day.
    
    
    • Children younger than 6 years of age—Use and dose must be determined by your doctor.
    
    
  
  

• For schizophrenia:
  
  • For oral dosage forms (tablets and orally disintegrating tablets):
    
    • Adults—At first, 10 to 15 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 30 mg per day.
    
    
    • Teenagers 13 to 17 years of age—At first, 2 mg once a day. The dose will be gradually increased to 10 mg once a day. Your doctor may adjust your dose again as needed. However, the dose is usually not more than 30 mg per day.
    
    
    • Children younger than 13 years of age—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Opened bottles of the oral liquid can be used for up to 6 months after opening, but not beyond the expiration date on the bottle.

Precautions While Using Abilify

It is very important that your doctor check the progress of you or your child at regular visits to allow for changes in your dose and to make sure this medicine is working properly. Blood tests may be needed to check for any unwanted effects.

For some patients, this medicine can increase thoughts of suicide. Tell your doctor right away if you or your child start to feel more depressed and have thoughts about hurting yourself. Report any unusual thoughts or behaviors that trouble you, especially if they are new or are getting worse quickly. Make sure the doctor knows if you or your child have trouble sleeping, get upset easily, have a big increase in energy, or start to act reckless. Also tell the doctor if you have sudden or strong feelings, such as feeling nervous, angry, restless, violent, or scared. Let the doctor know if you or anyone in your family has bipolar disorder (manic-depressive illness) or has tried to commit suicide.

This medicine may add to the effects of alcohol and other central nervous system (CNS) depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicines for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicines; prescription pain medicines or narcotics; medicines for seizures or barbiturates; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any CNS depressants while you or your child are taking this medicine.

Aripiprazole may cause drowsiness, trouble with thinking, or trouble with controlling movements. Make sure you know how you react to this medicine before you drive, use machines, or do other jobs that require you to be alert, well-coordinated, or able to think well.

Stop taking this medicine and check with your doctor right away if you or your child have any of the following symptoms while using this medicine: convulsions (seizures); difficulty with breathing; a fast heartbeat; a high fever; high or low blood pressure; increased sweating; loss of bladder control; severe muscle stiffness; unusually pale skin; or tiredness. These could be symptoms of a serious condition called neuroleptic malignant syndrome (NMS).

This medicine may cause tardive dyskinesia (a movement disorder) especially in elderly women. Stop using this medicine and check with your doctor right away if you or your child have any of the following symptoms while taking this medicine: lip smacking or puckering, puffing of the cheeks, rapid or worm-like movements of the tongue, uncontrolled chewing movements, or uncontrolled movements of the arms and legs.

Dizziness, lightheadedness, or fainting may occur, especially when you get up from a lying or sitting position. Getting up slowly may help. If this problem continues or gets worse, check with your doctor.

This medicine may make it more difficult for your body to cool down. It might reduce how much you sweat. Your body could get too hot if you do not sweat enough. If your body gets too hot, you might feel dizzy, weak, tired, or confused. You might have an upset stomach or vomit. Call your doctor if drinking cool water and moving away from the heat does not cool you down.

This medicine may increase the amount of sugar in your blood. Also, the oral liquid form contains sugar. Check with your doctor right away if you or your child have increased thirst or increased urination. If you have diabetes, you may notice a change in the results of your urine or blood sugar tests. If you have any questions, check with your doctor.

This medicine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.

This medicine may increase your weight. Your doctor may need to check your or your child's weight on a regular basis while you are using this medicine.

Do not change the dose or stop taking this medicine without checking first with your doctor.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines) and herbal or vitamin supplements.

Abilify Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

• Difficulty with speaking


• drooling


• loss of balance control


• muscle trembling, jerking, or stiffness


• restlessness


• shuffling walk


• stiffness of the limbs


• twisting movements of the body


• uncontrolled movements, especially of the face, neck, and back

Less common

• Blurred vision


• dizziness


• headache


• inability to move the eyes


• increased blinking or spasms of the eyelid


• nervousness


• pounding in the ears


• slow or fast heartbeat


• sticking out the tongue


• trouble with breathing or swallowing


• unusual facial expressions

Rare

• Convulsions


• fast heartbeat


• high fever


• high or low blood pressure


• increased sweating


• lip smacking or puckering


• loss of bladder control


• muscle spasm or jerking of all extremities


• puffing of the cheeks


• rapid or worm-like movements of the tongue


• severe muscle stiffness


• sudden loss of consciousness


• tiredness


• uncontrolled chewing movements


• uncontrolled movements of the arms and legs


• unusually pale skin

Incidence not known

• Hives or welts


• itching skin


• itching, puffiness, or swelling of the eyelids or around the eyes, face, lips, or tongue


• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs


• redness of the skin


• shortness of breath


• skin rash


• tightness in the chest


• unusual tiredness or weakness


• wheezing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Bigger, dilated, or enlarged pupils (black part of the eye)


• diarrhea


• fast, pounding, or irregular heartbeat or pulse


• increased sensitivity of the eyes to light


• lack or loss of strength


• nausea


• sleepiness or unusual drowsiness


• vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Acid or sour stomach


• anxiety


• belching


• blurred vision


• difficulty having a bowel movement (stool)


• dry mouth


• fear


• fever


• headache


• heartburn


• hyperventilation


• inability to sit still


• indigestion


• irritability


• lightheadedness


• need to keep moving


• nervousness


• rash


• runny nose


• shaking


• sleeplessness


• sore throat


• stomach discomfort, upset, or pain


• trouble sleeping


• unable to sleep


• weight gain

Less common

• Accidental injury


• bloating or swelling of the face, arms, hands, lower legs, or feet


• body aches or pain


• congestion


• coughing


• difficulty with moving


• dryness or soreness of throat


• hoarseness


• increased appetite


• increased salivation


• joint pain


• muscle aching or cramping


• muscle pains or stiffness


• rapid weight gain


• sneezing


• stuffy nose


• swollen joints


• tender, swollen glands in the neck


• tingling of the hands or feet


• tremor


• unusual weight gain or loss


• voice changes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Abilify side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Abilify resources

• Abilify Side Effects (in more detail)
• Abilify Use in Pregnancy & Breastfeeding
• Drug Images
• Abilify Drug Interactions
• Abilify Support Group
• 197 Reviews for Abilify - Add your own review/rating

• Abilify Monograph (AHFS DI)


• Abilify Consumer Overview


• Abilify MedFacts Consumer Leaflet (Wolters Kluwer)


• Abilify Prescribing Information (FDA)


• Abilify Discmelt Orally Disintegrating Tablets MedFacts Consumer Leaflet (Wolters Kluwer)


• Aripiprazole Professional Patient Advice (Wolters Kluwer)

Compare Abilify with other medications

• Agitated State
• Autism
• Bipolar Disorder
• Borderline Personality Disorder
• Depression
• Obsessive Compulsive Disorder
• Post Traumatic Stress Disorder
• Schizoaffective Disorder
• Schizophrenia
• Tourette's Syndrome

Flintstones Gummies Chewables

Pronunciation: MUL-ti-VYE-ta-min/MIN-er-als
Generic Name: Pediatric Multivitamin/Minerals
Brand Name: Examples include Cerovite Jr and Flintstones Gummies

Flintstones Gummies Chewables are used for:

Treating or preventing low levels of vitamins and minerals in the body. It may also be used for other conditions as determined by your doctor.

Flintstones Gummies Chewables are a vitamin and mineral supplement. It works by providing extra vitamins and minerals to the body when you do not get enough from your diet.

Do NOT use Flintstones Gummies Chewables if:

• you are allergic to any ingredient in Flintstones Gummies Chewables

Contact your doctor or health care provider right away if any of these apply to you.

Before using Flintstones Gummies Chewables:

Some medical conditions may interact with Flintstones Gummies Chewables. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances (eg, soy)


• if you have anemia, liver problems, metabolism problems, or phenylketonuria

Some MEDICINES MAY INTERACT with Flintstones Gummies Chewables. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Acitretin, anticoagulants (eg, warfarin), or fluorouracil because the risk of their side effects may be increased by Flintstones Gummies Chewables


• Doxycycline, hydantoins (eg, phenytoin), levodopa, penicillamine, or thyroid hormones (eg, levothyroxine) because their effectiveness may be decreased by Flintstones Gummies Chewables

This may not be a complete list of all interactions that may occur. Ask your health care provider if Flintstones Gummies Chewables may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Flintstones Gummies Chewables:

Use Flintstones Gummies Chewables as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Flintstones Gummies Chewables by mouth with or without food.


• Chew well before swallowing.


• If your brand of Flintstones Gummies Chewables contains iron, do not take an antacid within several hours before or after you take Flintstones Gummies Chewables.


• If you are also taking a bisphosphonate (eg, alendronate), cefdinir, methyldopa, a quinolone antibiotic (eg, ciprofloxacin), or a tetracycline antibiotic (eg, minocycline), ask your doctor or pharmacist how to take them with Flintstones Gummies Chewables.


• If you miss a dose of Flintstones Gummies Chewables for 1 or more days, there is no cause for concern. If your doctor recommended that you take it, try to remember your dose every day.

Ask your health care provider any questions you may have about how to use Flintstones Gummies Chewables.

Important safety information:

• Do not take large doses of vitamins while you use Flintstones Gummies Chewables unless your doctor tells you to.


• Some brands of Flintstones Gummies Chewables contain soy. If you are allergic to soy products, ask your pharmacist if your brand contains soy.


• Some of these products contain phenylalanine. If you must have a diet that is low in phenylalanine, ask your pharmacist if it is in your product.


• Flintstones Gummies Chewables should not be used in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed. These children may also have an increased risk of choking on Flintstones Gummies Chewables.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Flintstones Gummies Chewables while you are pregnant. It is not known if Flintstones Gummies Chewables are found in breast milk. If you are or will be breast-feeding while you use Flintstones Gummies Chewables, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Flintstones Gummies Chewables:

All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Flintstonesmies side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Flintstones Gummies Chewables:

Store Flintstones Gummies Chewables at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Flintstones Gummies Chewables out of the reach of children and away from pets.

General information:

• If you have any questions about Flintstones Gummies Chewables, please talk with your doctor, pharmacist, or other health care provider.


• Flintstones Gummies Chewables are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Flintstones Gummies Chewables. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Flintstones Gummies resources

• Flintstones Gummies Side Effects (in more detail)
• Flintstones Gummies Use in Pregnancy & Breastfeeding
• Flintstones Gummies Drug Interactions
• 0 Reviews for Flintstonesmies - Add your own review/rating

Compare Flintstones Gummies with other medications

• Vitamin/Mineral Supplementation and Deficiency

Formula B Plus

Pronunciation: MUL-ti-VYE-ta-mins/MIN-er-als
Generic Name: Multivitamins with Minerals
Brand Name: Examples include Centrum and Formula B Plus

Formula B Plus is used for:

Treating or preventing low levels of vitamins and minerals in the body. It may also be used for other conditions as determined by your doctor.

Formula B Plus is a vitamin and mineral supplement. It works by providing extra vitamins and minerals to the body when you do not get enough from your diet.

Do NOT use Formula B Plus if:

• you are allergic to any ingredient in Formula B Plus

Contact your doctor or health care provider right away if this applies to you.

Before using Formula B Plus:

Some medical conditions may interact with Formula B Plus. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have anemia, liver problems, or metabolism problems

Some MEDICINES MAY INTERACT with Formula B Plus. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Acitretin or anticoagulants (eg, warfarin) because the risk of their side effects may be increased by Formula B Plus


• Levodopa or penicillamine because their effectiveness may be decreased by Formula B Plus

This may not be a complete list of all interactions that may occur. Ask your health care provider if Formula B Plus may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Formula B Plus:

Use Formula B Plus as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Formula B Plus by mouth with or without food.


• If you are also taking a bisphosphonate (eg, alendronate), take Formula B Plus at least 2 hours after you take the bisphosphonate.


• If you are also taking a quinolone antibiotic (eg, ciprofloxacin) or tetracycline antibiotic (eg, minocycline), ask your doctor or pharmacist how to take them with Formula B Plus.


• If you miss a dose of Formula B Plus for 1 or more days, there is no cause for concern. If your doctor recommends that you take it, try to remember your dose every day.

Ask your health care provider any questions you may have about how to use Formula B Plus.

Important safety information:

• Do not take large doses of vitamins while you use Formula B Plus unless your doctor tells you to.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Formula B Plus while you are pregnant. It is not known if Formula B Plus is found in breast milk. If you are or will be breast-feeding while you use Formula B Plus, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Formula B Plus:

All medicines may cause side effects, but many people have no, or minor, side effects. No COMMON side effects have been reported with this product. Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Formula B Plus side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Formula B Plus:

Store Formula B Plus at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Formula B Plus out of the reach of children and away from pets.

General information:

• If you have any questions about Formula B Plus, please talk with your doctor, pharmacist, or other health care provider.


• Formula B Plus is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Formula B Plus. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Formula B Plus resources

• Formula B Plus Side Effects (in more detail)
• Formula B Plus Use in Pregnancy & Breastfeeding
• Formula B Plus Drug Interactions
• Formula B Plus Support Group
• 0 Reviews for Formula B Plus - Add your own review/rating

• B & O Monograph (AHFS DI)


• BACiiM Monograph (AHFS DI)


• BAL in Oil Monograph (AHFS DI)


• Baciguent topical Monograph (AHFS DI)


• Bacitracin Zinc eent Monograph (AHFS DI)


• Baclofen Monograph (AHFS DI)


• Bactocill Monograph (AHFS DI)


• Balsalazide Disodium Monograph (AHFS DI)


• Banzel Monograph (AHFS DI)


• Baraclude Monograph (AHFS DI)


• Basiliximab Monograph (AHFS DI)


• Beclomethasone Dipropionate Monograph (AHFS DI)


• Beconase AQ eent Monograph (AHFS DI)


• Belladonna Monograph (AHFS DI)


• Benazepril Hydrochloride Monograph (AHFS DI)


• BeneFIX Monograph (AHFS DI)


• Bentyl Monograph (AHFS DI)


• Benzedrex Monograph (AHFS DI)


• Benzocaine eent Monograph (AHFS DI)


• Benzonatate Monograph (AHFS DI)


• Benztropine Mesylate Monograph (AHFS DI)


• Bepotastine Besilate Monograph (AHFS DI)


• Beractant Monograph (AHFS DI)


• Besifloxacin Hydrochloride Monograph (AHFS DI)


• Beta Carotene Monograph (AHFS DI)


• Betagan Monograph (AHFS DI)


• Betamethasone Monograph (AHFS DI)


• Betamethasone Dipropionate topical Monograph (AHFS DI)


• Betaxolol Hydrochloride Monograph (AHFS DI)


• Bethanechol Chloride Monograph (AHFS DI)


• Betoptic S eent Monograph (AHFS DI)


• Bevacizumab Monograph (AHFS DI)


• Bexarotene Monograph (AHFS DI)


• Bexxar Monograph (AHFS DI)


• Bicalutamide Monograph (AHFS DI)


• Biltricide Monograph (AHFS DI)


• Bimatoprost Monograph (AHFS DI)


• Biperiden Hydrochloride Monograph (AHFS DI)


• Bisacodyl Monograph (AHFS DI)


• Bismuth Salts Monograph (AHFS DI)


• Bisoprolol Fumarate Monograph (AHFS DI)


• Bivalirudin Monograph (AHFS DI)


• Blenoxane Monograph (AHFS DI)


• Bleph 10 Monograph (AHFS DI)


• Boniva Monograph (AHFS DI)


• Bontril Monograph (AHFS DI)


• Bortezomib Monograph (AHFS DI)


• Bosentan Monograph (AHFS DI)


• Botox Monograph (AHFS DI)


• Botulinum Toxin Type B Monograph (AHFS DI)


• Brevibloc Monograph (AHFS DI)


• Brimonidine Tartrate Monograph (AHFS DI)


• Brinzolamide Monograph (AHFS DI)


• Bromfenac Sodium Monograph (AHFS DI)


• Bromocriptine Mesylate Monograph (AHFS DI)


• Brompheniramine Maleate, Dexbrompheniramine Maleate Monograph (AHFS DI)


• Brovana Monograph (AHFS DI)


• Budesonide Monograph (AHFS DI)


• Bulk-Forming Laxatives Monograph (AHFS DI)


• Bumetanide Monograph (AHFS DI)


• Bupivacaine Hydrochloride Monograph (AHFS DI)


• Buprenorphine Hydrochloride Monograph (AHFS DI)


• Bupropion Hydrochloride Monograph (AHFS DI)


• Buspirone Hydrochloride Monograph (AHFS DI)


• Busulfan Monograph (AHFS DI)


• Butenafine Hydrochloride Monograph (AHFS DI)


• Butoconazole Monograph (AHFS DI)


• Butorphanol Tartrate Monograph (AHFS DI)


• Byetta Monograph (AHFS DI)


• Bystolic Monograph (AHFS DI)


• Centratex Prescribing Information (FDA)


• Dacarbazine Monograph (AHFS DI)


• Daclizumab Monograph (AHFS DI)


• Dacogen Monograph (AHFS DI)


• Dactinomycin Monograph (AHFS DI)


• Dalfampridine Monograph (AHFS DI)


• Dalmane Monograph (AHFS DI)


• Dalteparin Sodium Monograph (AHFS DI)


• Danazol Monograph (AHFS DI)


• Dantrium Monograph (AHFS DI)


• Dapsone Monograph (AHFS DI)


• Daptomycin Monograph (AHFS DI)


• Daraprim Monograph (AHFS DI)


• Darbepoetin Alfa Monograph (AHFS DI)


• Darifenacin Hydrobromide Monograph (AHFS DI)


• Darunavir Monograph (AHFS DI)


• Dasatinib Monograph (AHFS DI)


• Decavac Monograph (AHFS DI)


• Declomycin Monograph (AHFS DI)


• Deferasirox Monograph (AHFS DI)


• Deferoxamine Mesylate Monograph (AHFS DI)


• Delavirdine Mesylate Monograph (AHFS DI)


• Demadex Monograph (AHFS DI)


• Demerol Monograph (AHFS DI)


• Denavir Monograph (AHFS DI)


• Denileukin Diftitox Monograph (AHFS DI)


• Denosumab Monograph (AHFS DI)


• DepoCyt Monograph (AHFS DI)


• Dermatop Monograph (AHFS DI)


• Desipramine Hydrochloride Monograph (AHFS DI)


• Desirudin Monograph (AHFS DI)


• Desloratadine Monograph (AHFS DI)


• Desmopressin Acetate Monograph (AHFS DI)


• Desonide Monograph (AHFS DI)


• Desoximetasone Monograph (AHFS DI)


• Desoxyn Monograph (AHFS DI)


• Desvenlafaxine Succinate Monograph (AHFS DI)


• Detrol Monograph (AHFS DI)


• Dexamethasone Monograph (AHFS DI)


• Dexamethasone Sodium Phosphate eent Monograph (AHFS DI)


• Dexlansoprazole Monograph (AHFS DI)


• Dexmedetomidine Hydrochloride Monograph (AHFS DI)


• Dexmethylphenidate Hydrochloride Monograph (AHFS DI)


• Dexrazoxane Hydrochloride Monograph (AHFS DI)


• Dextran 40 Monograph (AHFS DI)


• Dextran 70 Monograph (AHFS DI)


• Dextroamphetamine Monograph (AHFS DI)


• Dextromethorphan Hydrobromide Monograph (AHFS DI)


• Dextrose Monograph (AHFS DI)


• Dey-Pak Monograph (AHFS DI)


• Diabinese Monograph (AHFS DI)


• Diamox Monograph (AHFS DI)


• Diazepam Monograph (AHFS DI)


• Diazoxide Monograph (AHFS DI)


• Dibenzyline Monograph (AHFS DI)


• Dibucaine Monograph (AHFS DI)


• Dicloxacillin Sodium Monograph (AHFS DI)


• Didanosine Monograph (AHFS DI)


• Didronel Monograph (AHFS DI)


• Diethylpropion Hydrochloride Monograph (AHFS DI)


• Differin Monograph (AHFS DI)


• Diflorasone Diacetate Monograph (AHFS DI)


• Diflucan Monograph (AHFS DI)


• Diflunisal Monograph (AHFS DI)


• Difluprednate Monograph (AHFS DI)


• Digoxin Monograph (AHFS DI)


• Dihydroergotamine Mesylate Monograph (AHFS DI)


• Diltiazem Hydrochloride Monograph (AHFS DI)


• Dimenhydrinate Monograph (AHFS DI)


• Dinoprostone Monograph (AHFS DI)


• Dipentum Monograph (AHFS DI)


• Diphenhydramine Hydrochloride Monograph (AHFS DI)


• Diphenoxylate Hydrochloride Monograph (AHFS DI)


• Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed, Tetanus Toxoid and Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed Monograph (AHFS DI)


• Dipivefrin Hydrochloride Monograph (AHFS DI)


• Diprivan Monograph (AHFS DI)


• Dipyridamole Monograph (AHFS DI)


• Disopyramide Phosphate Monograph (AHFS DI)


• Disulfiram Monograph (AHFS DI)


• Diuril Monograph (AHFS DI)


• Divalproex Sodium Monograph (AHFS DI)


• Dobutamine Hydrochloride Monograph (AHFS DI)


• Docetaxel Monograph (AHFS DI)


• Docosanol Monograph (AHFS DI)


• Docusate Salts Monograph (AHFS DI)


• Dofetilide Monograph (AHFS DI)


• Dolasetron Mesylate Monograph (AHFS DI)


• Dolomite Natural MedFacts for Professionals (Wolters Kluwer)


• Dolomite Natural MedFacts for Consumers (Wolters Kluwer)


• Donepezil Hydrochloride Monograph (AHFS DI)


• Dopamine Hydrochloride Monograph (AHFS DI)


• Dopram Monograph (AHFS DI)


• Doribax Monograph (AHFS DI)


• Dornase Alfa Monograph (AHFS DI)


• Dorzolamide Hydrochloride Monograph (AHFS DI)


• Dostinex Monograph (AHFS DI)


• Dovonex Monograph (AHFS DI)


• Doxazosin Mesylate Monograph (AHFS DI)


• Doxepin Hydrochloride Monograph (AHFS DI)


• Doxercalciferol Monograph (AHFS DI)


• Doxorubicin Hydrochloride Monograph (AHFS DI)


• Doxycycline Monograph (AHFS DI)


• Doxycycline Calcium Monograph (AHFS DI)


• Doxylamine Succinate Monograph (AHFS DI)


• Drisdol Monograph (AHFS DI)


• Dronabinol Monograph (AHFS DI)


• Dronedarone Hydrochloride Monograph (AHFS DI)


• Droperidol Monograph (AHFS DI)


• Drotrecogin Alfa (Activated) Monograph (AHFS DI)


• Duloxetine Monograph (AHFS DI)


• Duricef Monograph (AHFS DI)


• Dutasteride Monograph (AHFS DI)


• Dyclonine Hydrochloride Monograph (AHFS DI)


• Dyrenium Monograph (AHFS DI)


• Eldertonic


• Hemocyte Plus Concise Consumer Information (Cerner Multum)


• Megavite Rx Prescribing Information (FDA)


• daunorubicin citrate Monograph (AHFS DI)


• diclofenac epolamine Monograph (AHFS DI)

Compare Formula B Plus with other medications

• Vitamin/Mineral Supplementation and Deficiency